USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P13224 USC-OGP 2-DE database:  P13224 P13224 General information about the entry View entry in simple text format Entry name GP1BB_HUMAN Primary accession number P13224 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Platelet glycoprotein Ib beta chain; Short=GP-Ib beta; Short=GPIb-beta; Short=GPIbB; AltName: Full=Antigen CD42b-beta; AltName: CD_antigen=CD42c; Flags: Precursor;. Gene name Name=GP1BB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0195: pI=4.63; Mw=25176 SPOT OGP-0202: pI=4.61; Mw=24298 SPOT OGP-0205: pI=4.57; Mw=23744 SPOT OGP-0207: pI=4.85; Mw=23562 Cross-references UniProtKB/Swiss-Prot P13224; GP1BB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GP1BB_HUMAN Primary accession number P13224 Secondary accession number(s) Q14422 Q8NG40 Sequence was last modified on  January 1, 1990 (version 1) Annotations were last modified on  March 15, 2017 (version 163) Name and origin of the protein Description RecName: Full=Platelet glycoprotein Ib beta chain; Short=GP-Ib beta; Short=GPIb-beta; Short=GPIbB; AltName: Full=Antigen CD42b-beta; AltName: CD_antigen=CD42c; Flags: Precursor; Gene name Name=GP1BB Encoded on Name=GP1BB Keywords 3D-structure; Alternative splicing; Bernard Soulier syndrome; Blood coagulation; Cell adhesion; Complete proteome; Direct protein sequencing; Disease mutation; Disulfide bond; Glycoprotein; Hemostasis; Leucine-rich repeat; Membrane; Phosphoprotein; Reference proteome; Signal; Transmembrane; Transmembrane helix. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J03259; AAA52594.1; -; mRNA EMBL AF006988; AAC39781.1; -; Genomic_DNA EMBL L20860; AAA20398.1; -; mRNA EMBL U59632; AAB93437.1; -; mRNA EMBL AB086231; BAC00777.1; -; Genomic_DNA CCDS CCDS42980.1; -. [P13224-1]; . PIR A54137; NBHUIB; . PIR I55604; I55604; . RefSeq NP_000398.1; NM_000407.4. [P13224-1]; . UniGene Hs.283743; -; . UniGene Hs.728762; -; . PDB 3REZ; X-ray; 2.35 A; A/B/C/D=26-146 PDB 3RFE; X-ray; 1.24 A; A/B=26-146 PDBsum 3REZ; -; . PDBsum 3RFE; -; . ProteinModelPortal P13224; -; . SMR P13224; -; . BioGrid 109074; 32; . IntAct P13224; 4; . MINT MINT-1530456; -; . STRING 9606.ENSP00000383382; -; . iPTMnet P13224; -; . PhosphoSitePlus P13224; -; . DMDM 121532; -; . OGP P13224; -; . MaxQB P13224; -; . PaxDb P13224; -; . PeptideAtlas P13224; -; . PRIDE P13224; -; . DNASU 2812; -; . Ensembl ENST00000366425; ENSP00000383382; ENSG00000203618. [P13224-1]; . GeneID 2812; -; . KEGG hsa:2812; -; . UCSC uc062bnf.1; human. [P13224-1]; . CTD 2812; -; . DisGeNET 2812; -; . GeneCards GP1BB; -; . HGNC HGNC:4440; GP1BB; . MalaCards GP1BB; -; . MIM 138720; gene; . MIM 231200; phenotype; . neXtProt NX_P13224; -; . OpenTargets ENSG00000203618; -; . Orphanet 567; 22q11.2 deletion syndrome; . Orphanet 274; Bernard-Soulier syndrome; . Orphanet 853; Fetal and neonatal alloimmune thrombocytopenia; . PharmGKB PA179; -; . eggNOG KOG0619; Eukaryota; . eggNOG COG4886; LUCA; . GeneTree ENSGT00530000064244; -; . HOGENOM HOG000060136; -; . HOVERGEN HBG051791; -; . InParanoid P13224; -; . KO K06262; -; . OMA YRDLRCA; -; . OrthoDB EOG091G0XGH; -; . PhylomeDB P13224; -; . Reactome R-HSA-140837; Intrinsic Pathway of Fibrin Clot Formation; . Reactome R-HSA-430116; GP1b-IX-V activation signalling; . Reactome R-HSA-75892; Platelet Adhesion to exposed collagen; . Reactome R-HSA-76009; Platelet Aggregation (Plug Formation); . SignaLink P13224; -; . SIGNOR P13224; -; . GeneWiki GP1BB; -; . GenomeRNAi 2812; -; . PRO PR:P13224; -; . Proteomes UP000005640; Chromosome 22; . Genevisible P13224; HS; . GO GO:0005887; C:integral component of plasma membrane; NAS:ProtInc; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0004888; F:transmembrane signaling receptor activity; NAS:ProtInc; . GO GO:0007596; P:blood coagulation; TAS:Reactome; . GO GO:0007597; P:blood coagulation; intrinsic pathway; TAS:Reactome GO GO:0007155; P:cell adhesion; IEA:UniProtKB-KW; . GO GO:0007166; P:cell surface receptor signaling pathway; NAS:ProtInc; . GO GO:0030168; P:platelet activation; NAS:UniProtKB; . Gene3D 3.80.10.10; -; 1; . InterPro IPR000483; Cys-rich_flank_reg_C; . InterPro IPR032675; L_dom-like; . InterPro IPR000372; LRRNT; . Pfam PF01463; LRRCT; 1; . SMART SM00082; LRRCT; 1; . SMART SM00013; LRRNT; 1; . SUPFAM SSF52058; SSF52058; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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